Isle of Palms South Vacations from $765
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Your Isle of Palms South Vacation
Take all the stress out of planning your next getaway with an Isle of Palms South vacation package. Immerse yourself in the sights and sounds of this appealing neighborhood and experience what it has to offer. Not sure where to go during your trip to Isle of Palms South? Nearby attractions like Jacksonville Beach Pier, Oceanfront Park and Adventure Landing are good places to begin. Stop dreaming and start doing. When you're ready to lock in your dream vacation to Isle of Palms South, Expedia is here to help.
The Latest Isle of Palms South Vacation Packages
Hammock Beach Golf Resort & Spa
Reviewed on Sep 21, 2026
Where to stay in Isle of Palms South
Downtown Jacksonville
Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.
Amelia City
While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.
Oceanfront
If you're spending some time in Oceanfront, Oceanfront Park and Northeast Florida Beaches are top sights worth seeing.
Southside
If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.
Sawgrass
Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.
Isle of Palms South Hotel Deals
Margaritaville Jacksonville Beach
"The rooms were clean and the staff was wonderful but there were a few issues we had during our stay."
Reviewed on Sep 21, 2026
Hyatt Regency Jacksonville
"The hotel was extremely overcrowded. I have never stayed at a hotel where I had to stand in line and wait 20 minutes for the elevators."
Reviewed on Sep 21, 2026
The Villas of Amelia Island
"There was only 1 working electrical outlet in the room and it was in the bathroom. The in room charger for electronics either didn't work or the electrical outlet for it (which was behind the headboard on the bed) also did not work. The view of the ocean and the closeness of the pool were definite ..."
Reviewed on Sep 20, 2026
Things to do
Amelia Island Floating Tiki Boat Cruise with BYOB Option
CraigCat Boat Tour from Fernandina Beach
